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Composite Integrative Passive Sampler (CIPS)
A single environmental sampling technology to measure nearly all of the chemicals we are exposed to in water
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The Problem

Conventional grab sampling

Conventional grab sampling of water can greatly misrepresent actual exposure to chemicals. Passive sampling (over many days to weeks) provides a more representative time-weighted average exposure

Atrazine in Stream at Edge of Field

Competing passive sampling technology

Competing passive sampling technology measures either water-soluble or fat-soluble chemicals, not both. This adds cost and complexity to chemical exposure measurement

THe Solution
Composite Integrative Passive Sampler (CIPS)
our technology allows you to catch and see what you're missing compared to traditional or competitors’ methods
CIPS is a truly novel and unique passive sampler. It is the only passive sampler that can capture the full range of organic chemicals in the environment
CIPS can be extracted in only 4mL of solvent and directly injected on GCMS or LCMS, providing incredible savings to your lab and better for the environment
Save time, money, and the environment while obtaining higher quality data
Composite Integrative Passive Sampler (CIPS)
Line SwooshCIPS Polymer Image
CIPS
Captures both polar and non-polar chemicals
A single CIPS captures aggregate of competing samplers
No complicated external membrane
Rugged, self-supporting polymer withstands harsh environments
Opaque to UV light – no photodegradation of sorbed chemicals
Extract needs no cleanup
Extraction requires only 4 mL of solvent
Other Passive Samplers
Captures only a select portion of chemicals
Need to use multiple sampler types
Many require external membrane
Many require exterior support and protection against the environment
Many are UV transparent and allow photodegradation of chemicals
Most require extract cleanup
Extraction requires large volumes of solvent
THe Data
CIPS delivers an unprecedented,
comprehensive measure of the chemical exposome
Capture more

CIPS Accumulates the Aggregate of LDPE, POCIS, and Grab Sample

Far more chemicals were detected using CIPS deployed in wastewater than with other PSDs or in a grab water sample

CIPS provides time-weighted average concentration equal to sequential daily grab samples, with much lower variability. Grab sampling could easily result in over- or under-estimating exposure. You would need to collect and analyze water samples every 1-2 days to obtain the same representative value as CIPS provides using only a single sample

Atrazine in Stream at Edge of Field

Atrazine concentrations change dramatically with time. CIPS deployed for 30 days captures a far more representative measure of exposure than a grab sample

Time-Integrated Data

Microcystin LR concentrations vary 1000-fold over the 10-day period the US EPA uses to assess for adverse human health effects. CIPS captures the time-weighted average of the dissolved phase MC-LR

PSD Type Comparison

CIPS data are comparable to the combined data of LDPE + POCIS

Quantitatively accumulates organic chemicals over log KOW range of < 0 - 8.3

Atrazine

PCB 153

Two of the most common existing passive samplers capture a very different range of chemicals. Low-density polyethylene (LDPE) captures non-polar, fat-soluble chemicals (log KOW > 3.5), while the polar organic chemical integrative sampler (POCIS) captures polar, water-soluble chemicals (log KOW < 3.0). In stark contrast, CIPS offers an unparalleled ability to capture both polar and non-polar chemicals with log KOW < 0 - 8.3

CIPS outperforms all other passive samplers

CIPS captures nearly the full range of organic chemicals regulated in drinking water and considered hazardous substances by the US EPA for the Superfund Program. No other passive sampler comes close to this performance

We have initial calibrations for over 500 chemicals, including PFAS, PCBs, PAHs and related heterocyclic compounds, pesticides & herbicides, pharmaceutical and consumer product chemicals, dioxins/furans, plasticizers, and other industrial chemicals

Performance reference compounds (PRCs)

PRCs can be used to account for environmental variables that have an effect on chemical uptake rates, such as water flow, temperature, and biofouling of the passive sampler

Deploy

Simply deploy in water for 1-30 days
can be used in air, sediment, soil, and biosoils

Capture

Polar and non-polar chemicals are captured
log KOW < 0 - 8.3

Extract & Analyze

Extract with only 4 ml of solvent
can use with LCMS, GCMS, or in vitro assays

Chemicals tentatively identified in water

Chemicals with
quantitative calibration

Chemicals over
log KOW Range

Deployment sites
worldwide

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Application

Testing Sites Across the Globe

Statera has been deploying our CIPS passive samplers at dozens of sites around the world

World Map
World Map Shadow

Locations:

Tijuana River

Transboundary movement of chemicals in Tijuana River

San Diego

Bioavailability of organic chemicals in water and sediment

Seattle

Fate and exposure to tire anti-degradants (6PPD)

Shanghai

Fate and exposure to tire anti-degradants (6PPD)

China

Transboundary movement of chemicals in Mekong and Red Rivers

Louisiana

Bioavailability of PAH and oxy-PAH in water and sediment

Gulf of Mexico

Fate and exposure to brevetoxins

China

Fate and exposure to microcystins

United States

Fate, exposure and bioavailability of PFAS

United States

Fate, exposure and bioavailability of pesticides

United States

Target and non-target analysis of the chemical exposome

United States

Target and non-target analysis of the chemical exposome

San Diego

Fate, exposure and bioavailability of pesticides

Philippines

Fate, exposure and bioavailability of pesticides

Philippines

Fate, exposure and bioavailability of aquaculture chemicals

Nigeria

Bioavailability of PAH and oxy-PAH in water and sediment

The CIPS are being used to assess:

Chronic time-weighted-average (TWA) exposure in water for over 500 chemicals spanning log KOW < 0 - 8.3

PAHs, PCBs, legacy and current use pesticides, PFAS, PPCP chemicals, HABs, 6PPD

Metabolites and degradation products, byproducts of disinfection and waste treatment

Organic chemical exposome using both target and non-target analysis with high resolution mass spectrometry

Transboundary movement of chemicals in Asia and North America

Harmful algal blooms toxins (HABs) in the US and Asia (microcystins, brevetoxins, domoic acid)

Chronic exposure to tire anti-degradants (6PPD and 6PPD-quinone)

Fate, exposure and bioavailability of organic chemicals in water, sediment soil, and biosolids

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Joshua Home

New York Times

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New York Times

Documentation

Passive Sampling

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